V45L (p.Val45Leu) variant of AGTRAP (Q6RW13)
V45L (p.Val45Leu) in AGTRAP (Q6RW13) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
V45L (p.Val45Leu) variant details
- p.Val45Leu
- ESP rs375907716
- ExAC rs375907716
- TOPMed rs375907716
- gnomAD rs375907716
- Missense
- Variant Prioritization Score for Impact Estimate 0.29
- REVEL 0.03
- ESM-1b 1.00
- AlphaMissense 0.33
- MetaLR 0.10
- MetaSVM -1.06
- CADD 16.40
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available