A46P (p.Ala46Pro) variant of AGTRAP (Q6RW13)
A46P (p.Ala46Pro) in AGTRAP (Q6RW13) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.62 / 1. The record also includes population frequency data and structural context.
A46P (p.Ala46Pro) variant details
- p.Ala46Pro
- ExAC rs749572710
- TOPMed rs749572710
- gnomAD rs749572710
- Missense
- Variant Prioritization Score for Impact Estimate 0.616
- REVEL 0.56
- ESM-1b 1.00
- AlphaMissense 0.88
- MetaLR 0.09
- MetaSVM -1.02
- CADD 26.20
- Most common in the Latino/Admixed American population (allele frequency 0.00013)
- Structural context available