V49L (p.Val49Leu) variant of AGTR1 (Type-1 angiotensin II receptor)
V49L (p.Val49Leu) in AGTR1 (Type-1 angiotensin II receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.82 / 1. The record also includes population frequency data and structural context.
V49L (p.Val49Leu) variant details
- p.Val49Leu
- ESP rs145575818
- ExAC rs145575818
- TOPMed rs145575818
- gnomAD rs145575818
- Missense
- Variant Prioritization Score for Impact Estimate 0.816
- REVEL 0.84
- CADD 25.80
- PolyPhen-2 0.97
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 4.4e-05)
- Structural context available