V40M (p.Val40Met) variant of AGTR1 (Type-1 angiotensin II receptor)
V40M (p.Val40Met) in AGTR1 (Type-1 angiotensin II receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data, published literature, and structural context.
V40M (p.Val40Met) variant details
- p.Val40Met
- gnomAD 3-148741153-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.463
- REVEL 0.23
- CADD 25.30
- PolyPhen-2 0.82
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available