T33I (p.Thr33Ile) variant of AGTR1 (Type-1 angiotensin II receptor)
T33I (p.Thr33Ile) in AGTR1 (Type-1 angiotensin II receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
T33I (p.Thr33Ile) variant details
- p.Thr33Ile
- gnomAD rs1355208421
- Missense
- Variant Prioritization Score for Impact Estimate 0.312
- REVEL 0.03
- CADD 17.60
- PolyPhen-2 0.01
- SIFT 0.86
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available