S6P (p.Ser6Pro) variant of AGTR1 (Type-1 angiotensin II receptor)
S6P (p.Ser6Pro) in AGTR1 (Type-1 angiotensin II receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data, published literature, and structural context.
S6P (p.Ser6Pro) variant details
- p.Ser6Pro
- gnomAD 3-148741051-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.285
- REVEL 0.27
- CADD 20.50
- PolyPhen-2 0.00
- SIFT 0.08
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available