S5P (p.Ser5Pro) variant of AGTR1 (Type-1 angiotensin II receptor)
S5P (p.Ser5Pro) in AGTR1 (Type-1 angiotensin II receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data, published literature, and structural context.
S5P (p.Ser5Pro) variant details
- p.Ser5Pro
- gnomAD 3-148741048-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.2
- REVEL 0.14
- CADD 16.20
- PolyPhen-2 0.28
- SIFT 0.14
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- Literature evidence available