S47R (p.Ser47Arg) variant of AGTR1 (Type-1 angiotensin II receptor)
S47R (p.Ser47Arg) in AGTR1 (Type-1 angiotensin II receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.48 / 1. The record also includes population frequency data and structural context.
S47R (p.Ser47Arg) variant details
- p.Ser47Arg
- gnomAD rs1478603789
- Missense
- Variant Prioritization Score for Impact Estimate 0.485
- REVEL 0.40
- CADD 23.10
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9.9e-06)
- Structural context available