L75M (p.Leu75Met) variant of AGTR1 (Type-1 angiotensin II receptor)
L75M (p.Leu75Met) in AGTR1 (Type-1 angiotensin II receptor) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.67 / 1. The record also includes population frequency data, published literature, and structural context.
L75M (p.Leu75Met) variant details
- p.Leu75Met
- rs762648315
- gnomAD 3-148741257-CTT-C
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.672
- CADD 26.60
- Most common in the Non-Finnish European population (allele frequency 5.4e-06)
- Structural context available
- Literature evidence available