L59P (p.Leu59Pro) variant of AGTR1 (Type-1 angiotensin II receptor)
L59P (p.Leu59Pro) in AGTR1 (Type-1 angiotensin II receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
L59P (p.Leu59Pro) variant details
- p.Leu59Pro
- ExAC rs751092458
- gnomAD rs751092458
- Missense
- Variant Prioritization Score for Impact Estimate 0.454
- REVEL 0.35
- CADD 22.80
- PolyPhen-2 0.01
- SIFT 0.14
- Most common in the South Asian population (allele frequency 0.00021)
- Structural context available