K58T (p.Lys58Thr) variant of AGTR1 (Type-1 angiotensin II receptor)
K58T (p.Lys58Thr) in AGTR1 (Type-1 angiotensin II receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.70 / 1. The record also includes population frequency data and structural context.
K58T (p.Lys58Thr) variant details
- p.Lys58Thr
- ExAC rs765903933
- gnomAD rs765903933
- Missense
- Variant Prioritization Score for Impact Estimate 0.697
- REVEL 0.75
- CADD 24.20
- PolyPhen-2 0.87
- SIFT 0.07
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available