K58E (p.Lys58Glu) variant of AGTR1 (Type-1 angiotensin II receptor)
K58E (p.Lys58Glu) in AGTR1 (Type-1 angiotensin II receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.69 / 1. The record also includes population frequency data and structural context.
K58E (p.Lys58Glu) variant details
- p.Lys58Glu
- gnomAD rs1350271075
- Missense
- Variant Prioritization Score for Impact Estimate 0.685
- REVEL 0.73
- CADD 24.20
- PolyPhen-2 0.78
- SIFT 0.07
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available