K12T (p.Lys12Thr) variant of AGTR1 (Type-1 angiotensin II receptor)
K12T (p.Lys12Thr) in AGTR1 (Type-1 angiotensin II receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
K12T (p.Lys12Thr) variant details
- p.Lys12Thr
- gnomAD rs896587204
- Missense
- Variant Prioritization Score for Impact Estimate 0.324
- REVEL 0.29
- CADD 17.90
- PolyPhen-2 0.00
- SIFT 0.56
- Most common in the Latino/Admixed American population (allele frequency 4.5e-05)
- Structural context available