I31S (p.Ile31Ser) variant of AGTR1 (Type-1 angiotensin II receptor)
I31S (p.Ile31Ser) in AGTR1 (Type-1 angiotensin II receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data, published literature, and structural context.
I31S (p.Ile31Ser) variant details
- p.Ile31Ser
- gnomAD 3-148741127-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.486
- REVEL 0.36
- CADD 27.50
- PolyPhen-2 0.68
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available