I2F (p.Ile2Phe) variant of AGTR1 (Type-1 angiotensin II receptor)
I2F (p.Ile2Phe) in AGTR1 (Type-1 angiotensin II receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
I2F (p.Ile2Phe) variant details
- p.Ile2Phe
- ESP rs372561921
- ExAC rs372561921
- TOPMed rs372561921
- gnomAD rs372561921
- Missense
- Variant Prioritization Score for Impact Estimate 0.184
- REVEL 0.10
- CADD 15.90
- PolyPhen-2 0.00
- SIFT 0.06
- Most common in the Ashkenazi Jewish population (allele frequency 0.0012)
- Structural context available