I27V (p.Ile27Val) variant of AGTR1 (Type-1 angiotensin II receptor)
I27V (p.Ile27Val) in AGTR1 (Type-1 angiotensin II receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
I27V (p.Ile27Val) variant details
- p.Ile27Val
- ExAC rs773385210
- gnomAD rs773385210
- Missense
- Variant Prioritization Score for Impact Estimate 0.304
- REVEL 0.11
- CADD 17.90
- PolyPhen-2 0.30
- SIFT 0.63
- Most common in the South Asian population (allele frequency 5.8e-05)
- Structural context available