I14V (p.Ile14Val) variant of AGTR1 (Type-1 angiotensin II receptor)
I14V (p.Ile14Val) in AGTR1 (Type-1 angiotensin II receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data, published literature, and structural context.
I14V (p.Ile14Val) variant details
- p.Ile14Val
- gnomAD 3-148741075-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.242
- REVEL 0.04
- CADD 18.20
- PolyPhen-2 0.00
- SIFT 0.53
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- Literature evidence available