F77I (p.Phe77Ile) variant of AGTR1 (Type-1 angiotensin II receptor)
F77I (p.Phe77Ile) in AGTR1 (Type-1 angiotensin II receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.72 / 1. The record also includes population frequency data, published literature, and structural context.
F77I (p.Phe77Ile) variant details
- p.Phe77Ile
- gnomAD 3-148741264-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.721
- REVEL 0.78
- CADD 26.60
- PolyPhen-2 0.99
- SIFT 0.02
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available