F66L (p.Phe66Leu) variant of AGTR1 (Type-1 angiotensin II receptor)
F66L (p.Phe66Leu) in AGTR1 (Type-1 angiotensin II receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data and structural context.
F66L (p.Phe66Leu) variant details
- p.Phe66Leu
- TOPMed rs1229680209
- gnomAD rs1229680209
- Missense
- Variant Prioritization Score for Impact Estimate 0.487
- REVEL 0.66
- CADD 23.60
- PolyPhen-2 0.95
- SIFT 0.01
- Most common in the African/African-American population (allele frequency 9e-05)
- Structural context available