F55L (p.Phe55Leu) variant of AGTR1 (Type-1 angiotensin II receptor)
F55L (p.Phe55Leu) in AGTR1 (Type-1 angiotensin II receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data, published literature, and structural context.
F55L (p.Phe55Leu) variant details
- p.Phe55Leu
- gnomAD 3-148741198-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.306
- REVEL 0.10
- CADD 20.60
- PolyPhen-2 0.01
- SIFT 0.65
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available