D74G (p.Asp74Gly) variant of AGTR1 (Type-1 angiotensin II receptor)
D74G (p.Asp74Gly) in AGTR1 (Type-1 angiotensin II receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.81 / 1. The record also includes population frequency data, published literature, and structural context.
D74G (p.Asp74Gly) variant details
- p.Asp74Gly
- gnomAD 3-148741256-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.809
- REVEL 0.92
- CADD 27.60
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available
- Literature evidence available