T133S (p.Thr133Ser) variant of AGT (Angiotensinogen)
T133S (p.Thr133Ser) in AGT (Angiotensinogen) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
T133S (p.Thr133Ser) variant details
- p.Thr133Ser
- ExAC rs771357989
- gnomAD rs771357989
- Missense
- Variant Prioritization Score for Impact Estimate 0.446
- REVEL 0.37
- CADD 19.30
- PolyPhen-2 0.12
- SIFT 0.83
- Most common in the Non-Finnish European population (allele frequency 3.6e-06)
- Structural context available