T133I (p.Thr133Ile) variant of AGT (Angiotensinogen)
T133I (p.Thr133Ile) in AGT (Angiotensinogen) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.66 / 1. The record also includes population frequency data and structural context.
T133I (p.Thr133Ile) variant details
- p.Thr133Ile
- ExAC rs771357989
- gnomAD rs771357989
- Missense
- Variant Prioritization Score for Impact Estimate 0.659
- REVEL 0.69
- CADD 26.40
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the South Asian population (allele frequency 2.3e-05)
- Structural context available