T133A (p.Thr133Ala) variant of AGT (Angiotensinogen)
T133A (p.Thr133Ala) in AGT (Angiotensinogen) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data and structural context.
T133A (p.Thr133Ala) variant details
- p.Thr133Ala
- ExAC rs780044023
- TOPMed rs780044023
- gnomAD rs780044023
- Missense
- Variant Prioritization Score for Impact Estimate 0.489
- REVEL 0.46
- CADD 25.00
- PolyPhen-2 0.48
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available