T128R (p.Thr128Arg) variant of AGT (Angiotensinogen)
T128R (p.Thr128Arg) in AGT (Angiotensinogen) is a missense change. Clinical records from EBI and UniProt describe it as benign. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
T128R (p.Thr128Arg) variant details
- p.Thr128Arg
- 1000Genomes rs34829218
- ESP rs34829218
- ExAC rs34829218
- TOPMed rs34829218
- Benign
- Missense
- Variant Prioritization Score for Impact Estimate 0.33
- REVEL 0.39
- CADD 18.30
- PolyPhen-2 0.83
- SIFT 0.01
- EBI: Benign (in dbSNP:rs34829218)
- UniProt: Benign (in dbSNP:rs34829218)
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available