T128M (p.Thr128Met) variant of AGT (Angiotensinogen)
T128M (p.Thr128Met) in AGT (Angiotensinogen) is a missense change. Clinical records from EBI and UniProt describe it as benign. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
T128M (p.Thr128Met) variant details
- p.Thr128Met
- rs34829218
- UniProt VAR 035431
- 1000Genomes rs34829218
- ESP rs34829218
- Benign
- Missense
- Variant Prioritization Score for Impact Estimate 0.229
- REVEL 0.27
- CADD 8.79
- PolyPhen-2 0.08
- SIFT 0.08
- EBI: Benign (in dbSNP:rs34829218)
- UniProt: Benign (in dbSNP:rs34829218)
- Most common in the HGDP:MAKRANI population (allele frequency 0.068)
- Structural context available