S68C (p.Ser68Cys) variant of AGT (Angiotensinogen)
S68C (p.Ser68Cys) in AGT (Angiotensinogen) is a missense change. Clinical records from ClinVar, EBI, and UniProt describe it as uncertain significance in the context of not provided. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes structural context.
S68C (p.Ser68Cys) variant details
- p.Ser68Cys
- rs753775475
- ClinGen CA345207403
- ClinVar RCV003048490
- Uncertain significance
- not provided
- Missense
- Variant Prioritization Score for Impact Estimate 0.437
- AlphaMissense 0.15
- MetaLR 0.42
- MetaSVM -0.45
- PolyPhen-2 0.24
- SIFT 0.03
- MutPred 0.34
- ClinVar: Uncertain significance (not provided)
- EBI: Variant of uncertain significance
- UniProt: Uncertain significance
- Structural context available