P53S (p.Pro53Ser) variant of AGT (Angiotensinogen)
P53S (p.Pro53Ser) in AGT (Angiotensinogen) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
P53S (p.Pro53Ser) variant details
- p.Pro53Ser
- ExAC rs142417928
- gnomAD rs142417928
- Missense
- Variant Prioritization Score for Impact Estimate 0.307
- REVEL 0.14
- CADD 8.02
- PolyPhen-2 0.02
- SIFT 0.21
- Most common in the Latino/Admixed American population (allele frequency 4.5e-05)
- Structural context available