P127S (p.Pro127Ser) variant of AGT (Angiotensinogen)
P127S (p.Pro127Ser) in AGT (Angiotensinogen) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.84 / 1. The record also includes population frequency data and structural context.
P127S (p.Pro127Ser) variant details
- p.Pro127Ser
- TOPMed rs1320269397
- gnomAD rs1320269397
- Missense
- Variant Prioritization Score for Impact Estimate 0.842
- REVEL 0.90
- CADD 24.90
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Middle Eastern population (allele frequency 0.00017)
- Structural context available