M96V (p.Met96Val) variant of AGT (Angiotensinogen)
M96V (p.Met96Val) in AGT (Angiotensinogen) is a missense change. Clinical records from ClinVar, EBI, and UniProt describe it as likely benign in the context of not provided. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
M96V (p.Met96Val) variant details
- p.Met96Val
- rs767370325
- ClinGen CA1448331
- ClinVar RCV002127639
- ExAC rs767370325
- Likely benign
- not provided
- Missense
- Variant Prioritization Score for Impact Estimate 0.14
- REVEL 0.20
- CADD 0.12
- PolyPhen-2 0.00
- SIFT 0.51
- ClinVar: Likely benign (not provided)
- EBI: Likely benign
- UniProt: Likely benign
- Most common in the Latino/Admixed American population (allele frequency 0.00013)
- Structural context available