L86P (p.Leu86Pro) variant of AGT (Angiotensinogen)
L86P (p.Leu86Pro) in AGT (Angiotensinogen) is a missense change. Clinical records from EBI and UniProt describe it as uncertain significance. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
L86P (p.Leu86Pro) variant details
- p.Leu86Pro
- rs61762540
- ESP rs61762540
- ExAC rs61762540
- TOPMed rs61762540
- Uncertain significance
- Missense
- Variant Prioritization Score for Impact Estimate 0.447
- AlphaMissense 0.35
- MetaLR 0.44
- MetaSVM -0.46
- PolyPhen-2 0.96
- SIFT 0.09
- EBI: Variant of uncertain significance
- UniProt: Uncertain significance
- Population evidence available
- Structural context available