L79P (p.Leu79Pro) variant of AGT (Angiotensinogen)
L79P (p.Leu79Pro) in AGT (Angiotensinogen) is a missense change. Clinical records from EBI and UniProt describe it as uncertain significance. The available variant effect predictions contribute to a CATVariant prioritization score of 0.54 / 1. The record also includes population frequency data and structural context.
L79P (p.Leu79Pro) variant details
- p.Leu79Pro
- Ensembl rs886046084
- Uncertain significance
- Missense
- Variant Prioritization Score for Impact Estimate 0.537
- REVEL 0.60
- CADD 21.10
- PolyPhen-2 0.98
- SIFT 0.26
- EBI: Variant of uncertain significance
- UniProt: Uncertain significance
- Most common in the REMAINING population (allele frequency 3.3e-05)
- Structural context available