L45M (p.Leu45Met) variant of AGT (Angiotensinogen)
L45M (p.Leu45Met) in AGT (Angiotensinogen) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data and structural context.
L45M (p.Leu45Met) variant details
- p.Leu45Met
- TOPMed rs1247118760
- gnomAD rs1247118760
- Missense
- Variant Prioritization Score for Impact Estimate 0.368
- REVEL 0.37
- CADD 22.30
- PolyPhen-2 0.88
- SIFT 0.06
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available