L34R (p.Leu34Arg) variant of AGT (Angiotensinogen)
L34R (p.Leu34Arg) in AGT (Angiotensinogen) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.78 / 1. The record also includes population frequency data and structural context.
L34R (p.Leu34Arg) variant details
- p.Leu34Arg
- gnomAD rs1162645963
- Missense
- Variant Prioritization Score for Impact Estimate 0.777
- REVEL 0.88
- CADD 26.20
- PolyPhen-2 0.94
- SIFT 0.00
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available