L13F (p.Leu13Phe) variant of AGT (Angiotensinogen)
L13F (p.Leu13Phe) in AGT (Angiotensinogen) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
L13F (p.Leu13Phe) variant details
- p.Leu13Phe
- ExAC rs753160167
- TOPMed rs753160167
- gnomAD rs753160167
- Missense
- Variant Prioritization Score for Impact Estimate 0.274
- REVEL 0.06
- CADD 11.30
- PolyPhen-2 0.04
- SIFT 0.13
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available