L139V (p.Leu139Val) variant of AGT (Angiotensinogen)
L139V (p.Leu139Val) in AGT (Angiotensinogen) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
L139V (p.Leu139Val) variant details
- p.Leu139Val
- TOPMed rs1178781977
- gnomAD rs1178781977
- Missense
- Variant Prioritization Score for Impact Estimate 0.451
- REVEL 0.49
- CADD 20.90
- PolyPhen-2 0.29
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available