L125F (p.Leu125Phe) variant of AGT (Angiotensinogen)
L125F (p.Leu125Phe) in AGT (Angiotensinogen) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
L125F (p.Leu125Phe) variant details
- p.Leu125Phe
- ESP rs376049907
- TOPMed rs376049907
- gnomAD rs376049907
- Missense
- Variant Prioritization Score for Impact Estimate 0.324
- REVEL 0.30
- CADD 15.70
- PolyPhen-2 0.32
- SIFT 0.11
- Most common in the African/African-American population (allele frequency 9.6e-05)
- Structural context available