I29L (p.Ile29Leu) variant of AGT (Angiotensinogen)
I29L (p.Ile29Leu) in AGT (Angiotensinogen) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
I29L (p.Ile29Leu) variant details
- p.Ile29Leu
- TOPMed rs943542473
- gnomAD rs943542473
- Missense
- Variant Prioritization Score for Impact Estimate 0.285
- REVEL 0.34
- CADD 21.50
- PolyPhen-2 0.10
- SIFT 0.01
- Most common in the Latino/Admixed American population (allele frequency 0.00013)
- Structural context available