H120P (p.His120Pro) variant of AGT (Angiotensinogen)
H120P (p.His120Pro) in AGT (Angiotensinogen) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data and structural context.
H120P (p.His120Pro) variant details
- p.His120Pro
- ExAC rs756283153
- gnomAD rs756283153
- Missense
- Variant Prioritization Score for Impact Estimate 0.148
- REVEL 0.18
- CADD 5.87
- PolyPhen-2 0.09
- SIFT 0.15
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available