G5R (p.Gly5Arg) variant of AGT (Angiotensinogen)
G5R (p.Gly5Arg) in AGT (Angiotensinogen) is a missense change. Clinical records from EBI and UniProt describe it as uncertain significance. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
G5R (p.Gly5Arg) variant details
- p.Gly5Arg
- ESP rs377164467
- ExAC rs377164467
- TOPMed rs377164467
- gnomAD rs377164467
- Uncertain significance
- Missense
- Variant Prioritization Score for Impact Estimate 0.2
- REVEL 0.26
- CADD 9.52
- PolyPhen-2 0.06
- SIFT 0.01
- EBI: Variant of uncertain significance
- UniProt: Uncertain significance
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available