G140E (p.Gly140Glu) variant of AGT (Angiotensinogen)
G140E (p.Gly140Glu) in AGT (Angiotensinogen) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.86 / 1. The record also includes population frequency data and structural context.
G140E (p.Gly140Glu) variant details
- p.Gly140Glu
- TOPMed rs1240735071
- gnomAD rs1240735071
- Missense
- Variant Prioritization Score for Impact Estimate 0.856
- REVEL 0.92
- CADD 24.80
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available