G132C (p.Gly132Cys) variant of AGT (Angiotensinogen)
G132C (p.Gly132Cys) in AGT (Angiotensinogen) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.61 / 1. The record also includes population frequency data and structural context.
G132C (p.Gly132Cys) variant details
- p.Gly132Cys
- TOPMed rs1663545413
- Missense
- Variant Prioritization Score for Impact Estimate 0.608
- REVEL 0.68
- CADD 25.00
- PolyPhen-2 1.00
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 5.4e-06)
- Structural context available