F58L (p.Phe58Leu) variant of AGT (Angiotensinogen)
F58L (p.Phe58Leu) in AGT (Angiotensinogen) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
F58L (p.Phe58Leu) variant details
- p.Phe58Leu
- ESP rs369750944
- ExAC rs369750944
- TOPMed rs369750944
- gnomAD rs369750944
- Missense
- Variant Prioritization Score for Impact Estimate 0.266
- REVEL 0.27
- CADD 13.00
- PolyPhen-2 0.03
- SIFT 0.06
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available