D71Y (p.Asp71Tyr) variant of AGT (Angiotensinogen)
D71Y (p.Asp71Tyr) in AGT (Angiotensinogen) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data and structural context.
D71Y (p.Asp71Tyr) variant details
- p.Asp71Tyr
- rs374540090
- NCI-TCGA Cosmic COSV6418
- ESP rs374540090
- ExAC rs374540090
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.455
- AlphaMissense 0.11
- MetaLR 0.49
- MetaSVM -0.37
- PolyPhen-2 0.23
- SIFT 0.05
- MutPred 0.33
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available
- Structural context available