C14F (p.Cys14Phe) variant of AGT (Angiotensinogen)
C14F (p.Cys14Phe) in AGT (Angiotensinogen) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
C14F (p.Cys14Phe) variant details
- p.Cys14Phe
- ExAC rs767783982
- gnomAD rs767783982
- Missense
- Variant Prioritization Score for Impact Estimate 0.313
- REVEL 0.21
- CADD 22.20
- PolyPhen-2 0.01
- SIFT 0.01
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available