A83T (p.Ala83Thr) variant of AGT (Angiotensinogen)
A83T (p.Ala83Thr) in AGT (Angiotensinogen) is a missense change. Clinical records from EBI and UniProt describe it as likely benign. The available variant effect predictions contribute to a CATVariant prioritization score of 0.06 / 1. The record also includes population frequency data and structural context.
A83T (p.Ala83Thr) variant details
- p.Ala83Thr
- TOPMed rs886046083
- gnomAD rs886046083
- Likely benign
- Missense
- Variant Prioritization Score for Impact Estimate 0.0597
- REVEL 0.06
- CADD 0.32
- PolyPhen-2 0.00
- SIFT 0.48
- EBI: Likely benign
- UniProt: Likely benign
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available