A74T (p.Ala74Thr) variant of AGT (Angiotensinogen)
A74T (p.Ala74Thr) in AGT (Angiotensinogen) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
A74T (p.Ala74Thr) variant details
- p.Ala74Thr
- ExAC rs775362851
- TOPMed rs775362851
- gnomAD rs775362851
- Missense
- Variant Prioritization Score for Impact Estimate 0.183
- REVEL 0.10
- CADD 12.20
- PolyPhen-2 0.01
- SIFT 0.53
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available