A74P (p.Ala74Pro) variant of AGT (Angiotensinogen)
A74P (p.Ala74Pro) in AGT (Angiotensinogen) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
A74P (p.Ala74Pro) variant details
- p.Ala74Pro
- ExAC rs775362851
- TOPMed rs775362851
- gnomAD rs775362851
- Missense
- Variant Prioritization Score for Impact Estimate 0.334
- REVEL 0.33
- CADD 18.40
- PolyPhen-2 0.56
- SIFT 0.23
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available