A122D (p.Ala122Asp) variant of AGT (Angiotensinogen)
A122D (p.Ala122Asp) in AGT (Angiotensinogen) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
A122D (p.Ala122Asp) variant details
- p.Ala122Asp
- gnomAD rs1663547116
- Missense
- Variant Prioritization Score for Impact Estimate 0.332
- REVEL 0.41
- CADD 12.90
- PolyPhen-2 0.75
- SIFT 0.40
- Most common in the South Asian population (allele frequency 0.00021)
- Structural context available