R4W (p.Arg4Trp) variant of AGRN (Agrin)
R4W (p.Arg4Trp) in AGRN (Agrin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data, published literature, and structural context.
R4W (p.Arg4Trp) variant details
- p.Arg4Trp
- rs1337682906
- gnomAD 1-1020182-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.271
- REVEL 0.18
- MetaLR 0.22
- MetaSVM -0.73
- CADD 19.40
- PolyPhen-2 0.04
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available